Search on: MIXED CONNECTIVE TISSUE DISEASE 
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Descriptor English:   Mixed Connective Tissue Disease 
Descriptor Spanish:   Enfermedad Mixta del Tejido Conjuntivo 
Descriptor Portuguese:   Doença Mista do Tecido Conjuntivo 
Synonyms English:   Connective Tissue Disease, Mixed
Sharp Syndrome  
Tree Number:   C17.300.540
Definition English:   A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. 
Indexing Annotation English:   disease entity: read definition & do not confuse with CONNECTIVE TISSUE DISEASES; DF: MCTD
History Note English:   79 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   9137 
Unique Identifier:   D008947 

Occurrence in VHL:
 

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